specifically for kids
"While more than 200 cancer drugs have been developed and approved for adults, 85 the FDA through December, 2024 has approved a total of 64 drugs for use in the treatment of childhood cancers. 57 of the drugs were originally approved only for adult use, then later for pediatrics also. Today we have seven drugs that were approved in the first instance for use in cancer treatment for children: Teniposide (1992 for ALL) use now discontinued by NCI, clofarabine (2004 for ALL), dinutuximab (2015 for NB), tisagenlecleucel (2017 for ALL), calaspargase pegol-mk (2018 for ALL), selumetinib (2020 for NF1), naxitamab (2020 for NB) and eflornithine (2023 for HRNB). 86. In addition, the FDA has approved 8 drugs that help to reduce the toxicity associated with certain cancer treatments."
Source: CAC2.org
95% of childhood cancer survivors suffer significant lifelong side effects.
Each year in the U.S., more than 40,000 kids are actively receiving cancer treatments, but the vast majority of these treatments are not designed for children.
Instead most children receive doses of treatments designed for adults — even though their cancers are completely different than adult cancers and ones that only kids get. We’re here to change it.
By funding critical breakthrough research, we can create gentler, child-first treatments that help kids beat cancer and still be kids.
Source: CAC2.org
Source: CAC2.org
Source: CAC2.org
Creating new treatments that are less-toxic and more effective.
With the help of our world-class medical advisory board, we seek out, identify and support the most promising research taking place in the field today.
When a proposal is selected, we fund research at our partner hospitals, where promising science can move forward into better treatments for kids everywhere in the shortest amount of time possible.
Each year, more than 300,000 kids are diagnosed with cancer worldwide.
Pediatric cancer diagnoses increase by nearly 1% per year, with no signs of slowing down. Each year, more and more kids will need access to child-friendly treatments. Every time we fund a better treatment, we don’t just benefit one child or one family, we provide a path to recovery for every child who will ever have that cancer… from now until forever.
Better Treatments.
Brighter Futures.
By removing the red tape that delays progress, we help new treatments reach kids faster.
By focusing on research for less toxic treatments, we can reduce the risk of downstream side effects later in life.
Research is designed to treat the cancers specific to kids, making them more effective than adult-first options.
Ivy
Ivy is two years old and was diagnosed with neuroblastoma in the summer of 2025. Despite beginning her second round of chemo, she continues to fill every room with joy, laughter and strength far beyond her years. She loves playing doctor, cooking in her play kitchen and trying on mom’s makeup — constant reminders of how resilient kids can be and why research for safer treatments is so critical.
Ben
Ben was diagnosed with stage 3 Wilms tumor at age 3½ and treated at The Children’s Hospital of Philadelphia. After relapsing just three months post-treatment, he faced another year of chemo and radiation — and won. Now 12 and cancer-free for over six years, Ben has raised more than $35,000 for childhood cancer research and hopes to become an oncologist one day.
Paislee
In July 2022, Paislee was diagnosed with B-cell acute lymphoblastic leukemia and began treatment immediately. A few weeks later, a bacterial infection from well water sent her into stage 4 septic shock, turning her recovery into a fight for her life. After months in the ICU, Paislee is now thriving and proudly rang her bell in 2024 — a true miracle and reminder of the importance of awareness.